We’re pioneering precision-based medicines to revolutionize the treatment of kidney diseases.
A global epidemic with an innovation gap
Chronic kidney disease (CKD) affects 780 million people globally–that’s one in every ten people. Progression to end-stage kidney disease is common, and severely impacts quality of life. Despite this, fewer than 1% of all research programs across the biopharmaceutical industry are focused on reducing the substantial burden of CKD.
Of all active pipeline programs in the biopharmaceutical industry are for kidney diseases
Our Precision Medicine Approach to Treat Kidney Disease
We are applying precision medicine to discover, develop and commercialize disease-modifying kidney disease treatments. We believe our approach enables us to uncover subsets of patients based on genetic and environmental factors within heterogenous kidney diseases.
We have a robust pipeline of novel, precision medicine product candidates targeting kidney diseases with significant unmet medical needs. Our lead program, GFB-887, is designed to treat people with focal segmental glomerulosclerosis (FSGS) caused by an overactivation of the TRPC5-Rac1 pathway.
We aspire to be the world’s leading precision medicine kidney company – dedicated to our mission, focused on pursuing world-class science and fully committed to improving the lives of people with kidney disease.