
Finally, kidney disease meets a true opponent
We’re pioneering precision-based medicines to revolutionize the treatment of kidney diseases.
Our
Proteinuria in FSGS
Fact Stack
We’re excited to launch our Proteinuria in FSGS Fact Stack! This is designed to be a ‘bite-sized’ education campaign to help explain the role that proteinuria plays in Focal Segmental Glomerulosclerosis (FSGS) and its use as a clinically meaningful endpoint to assess investigational kidney disease therapeutics, like GFB-887, our lead precision medicine candidate. Click through each fact!
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A global epidemic with an innovation gap
Chronic kidney disease (CKD) affects 780 million people globally–that’s one in every ten people. Progression to end-stage kidney disease is common, and severely impacts quality of life. Despite this, fewer than 1% of all research programs across the biopharmaceutical industry are focused on reducing the substantial burden of CKD.
Learn more about the problem we aim to solvePeople worldwide with CKD
People die annually from kidney disease worldwide
Of all active pipeline programs in the biopharmaceutical industry are for kidney diseases
Our Precision Medicine Approach to Treat Kidney Disease, Starting with FSGS
We are applying precision medicine to discover, develop and commercialize disease-modifying kidney disease treatments. We believe our approach enables us to uncover subsets of patients based on genetic and environmental factors within heterogenous kidney diseases.
We have a robust pipeline of novel, clinical-stage, precision medicine product candidates, including or lead program, GFB-887 for TRPC5-mediated FSGS, and other kidney diseases. All of our programs target kidney diseases with significant unmet medical needs

Our Precision Medicine Product Engine: Integrating Kidney Genetics & Biology
Our product engine allows us to discover, validate and drug novel targets while identifying FSGS and kidney disease patient subsets most likely to respond to our treatments.
A bold mission to transform the lives of people living with FSGS and other kidney diseases
Our Mission
To deliver disease-modifying precision medicines that bring hope and renewed quality of life to people living with kidney diseases.
Our Vision
We aspire to save kidneys and end dialysis.
The Feeder Interview Series
Check out our new interview series, The Feeder. We’re speaking with people impacted by kidney disease, and a wide range of experts who are driving change, innovation and hope in the kidney space.
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Join Us!
We aspire to be the world’s leading precision medicine kidney company – dedicated to our mission, focused on pursuing world-class science and fully committed to improving the lives of people with FSGS and other kidney diseases.
