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Careers

At Goldfinch, we are pioneering a new approach to discover and develop precision medicines for kidney disease. Where others see risk, we see opportunity to make an impact and redefine the standard of care for patients with kidney disease. We recognize the importance of collaboration, and strive to work alongside people with kidney diseases, their families and clinicians to develop innovative treatments for conditions where no approved therapies exist.

We’re looking for teammates who relish the challenge, and are compelled to leave a positive mark on the lives of colleagues and the patients we serve alike. If this sounds like the community you want to grow with, we invite you to explore our current career opportunities below.

Scientist I/II, Biology Toggle

Job Summary

The Scientist I/II, Biology candidate should have strong image acquisition and image analysis skills across a  variety of different systems and/or iPSC and organoid differentiation experience. They will develop, implement and execute in vitro assays required for the advancement of high priority projects and Goldfinch Bio's Product Engine. This position is part of a close-knit  team focused on developing cutting edge assays for target validation and compound screening using in vitro models including human-derived kidney organoids.

Job Responsibilities

  • Development and implementation of a diverse set of cellular assays used to support lead discovery and target validation with an emphasis on image-based assays
  • Develop image analysis methods and maintain imaging systems
  • Keep up with the literature and design, execute, troubleshoot, and interpret biological experiments in support of program objectives in partnership with scientific leadership
  • Contribute significantly to tissue   culture work required for pipeline 2D and 3D cellular models
  • Interact and communicate results and conclusions to the biology team and cross-functional project teams

Required Skills & Qualifications

  • B.S. or M.S. in cell and/or molecular biology with minimum of 5 years of pharmaceutical/industry experience required OR Ph.D. with a minimum of 2 years experience 
  • Significant experience in
    • confocal imaging, high-content imaging; 
    • histological and immunofluorescence techniques
    • variety of image analysis methods (e.g. ImageJ/Fiji, Zen, Elements); familiarity with computational data analysis and/or Amira desirable but not required
  • Experience in cell and biochemical assay development and familiarity with high-throughput screens
  • Experience in biochemistry, molecular biology, and cell biology techniques
  • Extensive and diverse tissue culture experience; iPSC and organoid experience is desirable 
  • Demonstrated ability to thrive in a team environment
  • Good communicator
  • Some weekend work will be required
Senior/Principal Scientist, Biology Toggle

Job Summary

We’re seeking a highly motivated Senior Scientist or Principal Scientist with a strong background in renal biology to join our Biology Department and contribute to building our pipeline for renal diseases. The successful candidate will focus on driving scientific research to establish and validate novel targets for kidney disease. Responsibilities include leading and mentoring a team of scientists, development, characterization and implementation of models of kidney disease based on human biology, and implementing models for evaluation of potential therapeutics.

Job Responsibilities

  • Collaborate with scientists in cross-functional teams to discover tractable, high-impact disease targets.
  • Develop strategy and scientific approach to establish and characterize novel targets for kidney disease.
  • Establish in vitro assays to evaluate dose/response relationships, efficacy, and characterize molecules for potential therapeutic effects.
  • Initiate and manage external research collaborations to further the applications of in vitro models of chronic kidney disease.
  • Lead a group of researchers within Biology, providing guidance and mentorship.
  • Prepare, review and deliver high quality scientific presentations for internal/external use.
  • Commit to helping the team achieve deliverables and meet aggressive timelines.

Required Skills & Qualifications

  • PhD with at least 5 years post-degree research in the kidney disease field, translational experience is an asset. Prior work industry experience is an advantage but is not required.
  • Extensive hands-on experience with cell culture, in vitro and/or in vivo models of kidney disease.
  • Hands-on experience in cellular and biochemical techniques including standard molecular biology and protein biochemistry methods and proven assay troubleshooting skills.
  • Hands on experience in the development and validation of cell-based assays.
  • Experience with iPSCs and organoids is desirable.
  • Strong publication record and demonstrated experience conducting independent research.
  • Strong leadership and evidence of strategic scientific thinking.
  • Effective managerial skills and prior experience mentoring junior scientists with different skill sets.
Senior Research Associate/Scientist, Biology Toggle

Job Summary

We’re looking for a highly motivated Senior Research Associate or Scientist with a strong background in cell culture and molecular and cellular biology to join our Biology Department and contribute to building our pipeline for renal diseases. The successful candidate will support the new target discovery efforts by maintaining and differentiating iPSCs and other cell lines, performing experiments, and managing the laboratory’s inventory.

Job Responsibilities

  • Maintain cell lines including iPSCs and implementing new differentiation protocols. 
  • Perform well-designed and executed cellular and molecular biology experiments to enable data-driven decisions on program progression. 
  • Manage the laboratory’s inventory and put in place a system for efficient registration of materials and samples. 
  • Collaborate with cross-functional teams to support exploratory drug discovery and development. 
  • Prepare presentations for lab meetings and other internal and occasionally external collaborations. 
  • Commit to helping the team achieve deliverables and meet aggressive timelines.

Required Skills & Qualifications

  • B.S. or M.S. in a relevant field. Industry experience is desirable but not required. 
  • Extensive hands-on experience in cell culture of iPSCs and other lines is necessary.
  • Hands-on experience in cellular and biochemical techniques including standard molecular biology or protein biochemistry methods.
  • Familiarization with inventory management programs.
  • Excellent organizational skills and attention to details.
  • Demonstrated ability to thrive in a team environment
Chief Scientific Officer Toggle

Job Summary

Company Overview: Goldfinch Bio is a biotechnology company solely focused on pioneering precision-based kidney medicines. Building on recent breakthroughs in genetics and human biology to generate an unparalleled understanding of the biological pathways that drive kidney disease, we are uniquely positioned to translate these discoveries into new therapies that target the molecular causes for diseases of the kidney and bring new therapeutics to a severely underserved patient population. Goldfinch Bio was launched in 2016 by Third Rock Ventures, and is headquartered in Cambridge, Massachusetts. For more information, please visit https://www.goldfinchbio.com.

The Role: The Chief Scientific Officer for Goldfinch Bio will be responsible for all aspects of research, including drug discovery, biology, biomarkers and discovery DMPK, in addition to the Kidney Genome Atlas (KGA). Reporting directly to the President & Chief Executive Officer, this individual will build and lead a cross-functional team of scientists in drug discovery including discovery DMPK, biology, biomarkers and genomics. As a member of the Executive Leadership Team, the CSO will be the internal and external face of science and technology representing the company in public speaking engagements and with the Scientific Advisory Board, Board of Directors, and investors.

Job Responsibilities

  • Serve as a strategic business partner to the CEO; act as a key member of the executive team and participate in corporate business initiatives including financial and strategic campaigns, key collaborations, and partnerships.
  • Provide world class scientific input into the company’s R&D programs to support overall corporate strategy; define research strategy that clearly connects with business value; step outside of core research ideas and circles to contribute more broadly to company direction.
  • Design and implement the company’s strategic research roadmap, including the oversight of intellectual property initiatives, filing of patents, and development of grant applications; speak effectively about research pipeline and progress with platforms.
  • Build, lead, manage and develop top-performing research teams in drug discovery, discovery DMPK, biology, biomarkers and genomics.
  • Drive research towards clinical development, executing on aggressive timelines and effectively utilizing resources; advance multiple candidates from research to clinical development in industry-leading timelines.
  • Inspire cross-functional connectivity and collaboration across research teams and between research and development teams.
  • Provide peers and staff with continuous scientific input in the areas of business development, product development, financial planning, regulatory affairs, manufacturing, and other initiatives.
  • Demonstrate organizational leadership and show the ability to drive results by tracking and reporting on project initiatives, chairing weekly meetings, and issuing meeting summaries as appropriate.
  • Build an elite research team that will set a new standard and develop the skills of the team.
  • Ensure that the research organization is producing the highest quality science in all aspects.
  • Ensure that intellectual property generated in R&D is captured, documented, and appropriately filed to maximize value for Goldfinch Bio.
  • Present our science effectively at critical external meetings and fora.
  • Work collaboratively within the organization; develop areas of expertise needed to pursue the company’s scientific & product goals.
  • Meet deadlines consistently including reporting and preparation of scientific presentations for the BOD, investors, journal editorial boards and conference scientific editors.
  • Attend relevant BOD, investor, scientific and other meetings as appropriate and present summaries of the company’s scientific achievements and technology roadmap; serve as chief spokesperson for science strategy, translating the company science into understandable concepts for diverse audiences including the BOD, investors, clinical partners, industry, advisors, etc.
  • Nurture and develop scientific talent into world class drug discovery leaders.
  • Help develop a broad set of strategic partnerships with leading experts.
  • Build and manage research budgets and allocation for scientific programs.

Required Skills & Qualifications

  • PhD or MD/PhD
  • Strong technical biology experience
  • Kidney research experience
  • Deep scientific expertise in the critical disciplines required to discover and develop new therapies
  • Established track record of scientific and product development achievements from discovery to clinical development; small molecule experience
  • Ability to take complicated scientific concepts and effectively communicate them to a broad range of audiences
  • Ability to help drive and lead company from research point of view and contribute to broader company strategy
  • Experience using innovative technologies, platforms, and modalities to advance novel drug candidates
  • Appreciation for the design, organization, and execution of a successful scientific and clinical approach and working knowledge of regulatory, commercial, and business aspects of biotech industry
  • Expertise in leading research organizations and scaling to meet company needs
  • Experience in developing & delivering life science products and/or services
  • Demonstrated ability to work closely and successfully with strategic partners
  • Experience in effectively managing budgets
  • Prior involvement in technology and product licensing
  • Excellent leadership skills
  • Excellent oral, written, and interpersonal communication skills
  • Ability to collaborate with a team and think creatively as an individual
  • Ability to maintain confidentiality and demonstrate high degree of integrity, excellent organizational skills and superior reliability and responsibility

 

Qualified and interested executives should contact our search partner, Kim Wilson, VP Executive Search with Slone Partners, at the following email address: Kimd@slonepartners.com