Publications & Presentations

Publication

Discovery of a Potent and Selective TRPC5 Inhibitor, Efficacious in a Focal Segmental Glomerulosclerosis Model

Maolin Yu, Mark W. Ledeboer, Matthew Daniels, Goran Malojcic, Thomas T. Tibbitts, Marie Coeffet-Le Gal, Xin-Ru Pan-Zhou, Amy Westerling-Bui, Maria Beconi, John F. Reilly, Peter Mundel, and Jean-Christophe Harmange

Publication

Structural basis of TRPC4 regulation by calmodulin and pharmacological agents

Deivanayagabarathy Vinayagam, Dennis Quentin, Jing Yu-Strzelczyk, Oleg Sitsel, Felipe Merino, Markus Stabrin, Oliver Hofnagel, Maolin Yu, Mark W Ledeboer, Georg Nagel, Goran Malojcic, Stefan Raunser

Publication

Proteinuria Reduction and Kidney Survival in Focal Segmental Glomerulosclerosis

Jonathan P. Troost, Howard Trachtman, Cathie Spino, Frederick J. Kaskel, Aaron Friedman, Marva M. Moxey-Mims, Richard N. Fine, Jennifer J. Gassman, Jeffrey B. Kopp, Liron Walsh, Rong Wang, Debbie S. Gipson

Poster

Generation of Collecting Duct Kidney Organoids from hiPSC

Sergii Kyrychenko, Xiang Pan, Eva Maria Fast, Alyssa B. Fanelli, Henrietta Bennet, Maria Lalioti, John F. Reilly, Peter Mundel, Amy Duyen Westerling-Bui

  • 2020 American Society of Nephrology Kidney Week
  • October 22-25, 2020
  • Virtual
Poster

GFB-887, a TRPC5 Inhibitor, Is Safe, Well Tolerated and Engages the TRPC5 Target Leading to Reductions in Urinary RAC1 After Single Doses in Healthy Volunteers

Liron Walsh, Chris Lynam, Leslie Johnson, Tingting Ge, Xin-Ru Pan-Zhou, Frank Czerwiec, Yossi Dagon, Hari Raghu, John F. Reilly

  • 2020 American Society of Nephrology Kidney Week
  • October 22-25, 2020
  • Virtual